HNRPDL Antibody

HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HNRPDL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

HNRPDL antibody can be used for detection of HNRPDL by ELISA at 1:12500. HNRPDL antibody can be used for detection of HNRPDL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.