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KHSRP Antibody

Product Specifications

Background

KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) .It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

NCBI Gene ID

8570

Swiss Prot

Q92945

Accession Number

NP_003676

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHSRP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KHSRP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

73 kDa

Applications Notes

KHSRP antibody can be used for detection of KHSRP by ELISA at 1:1562500. KHSRP antibody can be used for detection of KHSRP by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

KHSRP

NCBI Official Name

KH-type splicing regulatory protein

NCBI Organism

Homo sapiens

Background Reference 01

Winzen, R., (2007) Mol. Cell. Biol. 27 (23), 8388-8400.

Other Product Names

KHSRP, FBP2, FUBP2, KSRP, MGC99676

Tested Applications

ELISA, WB

Protein ID

154355000

Physical Properties

Liquid

Frequently Asked Questions

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