KHSRP Antibody
Product Specifications
Background
KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) .It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
NCBI Gene ID
8570
Swiss Prot
Q92945
Accession Number
NP_003676
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHSRP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KHSRP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-616
Calculated Molecular Weight
73 kDa
Applications Notes
KHSRP antibody can be used for detection of KHSRP by ELISA at 1:1562500. KHSRP antibody can be used for detection of KHSRP by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KHSRP
NCBI Official Name
KH-type splicing regulatory protein
NCBI Organism
Homo sapiens
Background Reference 01
Winzen, R., (2007) Mol. Cell. Biol. 27 (23), 8388-8400.
Other Product Names
KHSRP, FBP2, FUBP2, KSRP, MGC99676
Tested Applications
ELISA, WB
Protein ID
154355000
Physical Properties
Liquid
Curated Selection
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