SNRPB Antibody
Product Specifications
Background
SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
NCBI Gene ID
6628
Swiss Prot
Q66K91
Accession Number
NP_003082
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNRPB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SNRPB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-613
Calculated Molecular Weight
24 kDa
Applications Notes
SNRPB antibody can be used for detection of SNRPB by ELISA at 1:312500. SNRPB antibody can be used for detection of SNRPB by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SNRPB
NCBI Official Name
Small nuclear ribonucleoprotein polypeptides B and B1
NCBI Organism
Homo sapiens
Background Reference 01
Ong, S.E., (2004) Nat. Methods 1 (2), 119-126.
Other Product Names
SNRPB, COD, SNRPB1, SmB/SmB', snRNP-B, SmB/B', Sm-B/B'
Tested Applications
ELISA, WB
Protein ID
4507125
Physical Properties
Liquid
Curated Selection
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