JMJD3 Antibody
Product Specifications
Background
JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
NCBI Gene ID
23135
Swiss Prot
O15054
Accession Number
NP_001073893
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JMJD3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store JMJD3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
181 kDa
Applications Notes
JMJD3 antibody can be used for detection of JMJD3 by ELISA at 1:312500. JMJD3 antibody can be used for detection of JMJD3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KDM6B
NCBI Official Name
Lysine (K) -specific demethylase 6B
NCBI Organism
Homo sapiens
Background Reference 01
Hong, S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18439-18444.
Other Product Names
JMJD3, KIAA0346, JMJD3
Tested Applications
ELISA, WB
Protein ID
122937251
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
