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MSL3L1 Antibody

Product Specifications

Background

MSL3L1 is a nuclear protein, which is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.

NCBI Gene ID

10943

Swiss Prot

Q8N5Y2

Accession Number

NP_523353

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSL3L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MSL3L1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

60 kDa

Applications Notes

MSL3L1 antibody can be used for detection of MSL3L1 by ELISA at 1:62500. MSL3L1 antibody can be used for detection of MSL3L1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MSL3

NCBI Official Name

Male-specific lethal 3 homolog (Drosophila)

NCBI Organism

Homo sapiens

Background Reference 01

Smith, E.R., (2005) Mol. Cell. Biol. 25 (21), 9175-9188.

Other Product Names

MSL3L1, DKFZP586J1822, MSL3L1

Tested Applications

ELISA, WB

Protein ID

212275945

Physical Properties

Liquid

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