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ARNTL2 Antibody

Product Specifications

Background

ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.

NCBI Gene ID

56938

Swiss Prot

Q8WYA1

Accession Number

NP_064568

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARNTL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1219 - MCF7 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ARNTL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

71 kDa

Applications Notes

ARNTL2 antibody can be used for detection of ARNTL2 by ELISA at 1:1562500. ARNTL2 antibody can be used for detection of ARNTL2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ARNTL2

NCBI Official Name

Aryl hydrocarbon receptor nuclear translocator-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Shi, J., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press.

Other Product Names

ARNTL2, BMAL2, CLIF, MGC149671, MGC149672, MOP9, PASD9, bHLHe6

Tested Applications

ELISA, WB

Protein ID

31745180

Physical Properties

Liquid

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