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HBP1 Antibody

Product Specifications

Background

HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.

NCBI Gene ID

26959

Swiss Prot

O60381

Accession Number

NP_036389

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HBP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HBP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

58 kDa

Applications Notes

HBP1 antibody can be used for detection of HBP1 by ELISA at 1:1562500. HBP1 antibody can be used for detection of HBP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HBP1

NCBI Official Name

HMG-box transcription factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Paulson, K.E., (2007) Cancer Res. 67 (13), 6136-6145.

Other Product Names

HBP1, FLJ16340

Tested Applications

ELISA, WB

Protein ID

21361411

Physical Properties

Liquid

Frequently Asked Questions

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