HBP1 Antibody
Product Specifications
Background
HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
NCBI Gene ID
26959
Swiss Prot
O60381
Accession Number
NP_036389
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HBP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-467
Calculated Molecular Weight
58 kDa
Applications Notes
HBP1 antibody can be used for detection of HBP1 by ELISA at 1:1562500. HBP1 antibody can be used for detection of HBP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HBP1
NCBI Official Name
HMG-box transcription factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Paulson, K.E., (2007) Cancer Res. 67 (13), 6136-6145.
Other Product Names
HBP1, FLJ16340
Tested Applications
ELISA, WB
Protein ID
21361411
Physical Properties
Liquid
Curated Selection
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