MLLT3 Antibody
Product Specifications
Background
MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22; q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
NCBI Gene ID
4300
Swiss Prot
P42568
Accession Number
NP_004520
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLLT3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MLLT3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
63 kDa
Applications Notes
MLLT3 antibody can be used for detection of MLLT3 by ELISA at 1:1562500. MLLT3 antibody can be used for detection of MLLT3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MLLT3
NCBI Official Name
Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 3
NCBI Organism
Homo sapiens
Background Reference 01
Wei, J., (2008) Cancer Cell 13 (6), 483-495.
Other Product Names
MLLT3, AF9, FLJ2035, YEATS3
Tested Applications
ELISA, WB
Protein ID
156104889
Physical Properties
Liquid
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