ONECUT1 Antibody
Product Specifications
Background
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
NCBI Gene ID
3175
Swiss Prot
Q9UBC0
Accession Number
NP_004489
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ONECUT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ONECUT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
ONECUT1 antibody can be used for detection of ONECUT1 by ELISA at 1:312500. ONECUT1 antibody can be used for detection of ONECUT1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ONECUT1
NCBI Official Name
One cut homeobox 1
NCBI Organism
Homo sapiens
Background Reference 01
Jiang, X., (2008) Oncol. Rep. 19 (1), 157-163.
Other Product Names
ONECUT1, HNF-6, HNF6, HNF6A
Tested Applications
ELISA, WB
Protein ID
24307887
Physical Properties
Liquid
Curated Selection
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