ZNF141 Antibody

Zinc finger encoding genes would be good candidates for being involved in the multiple developmental defects associated with chromosomal aneusomy--because of their role as transcriptional regulators, their abundance in the genome and their known association with specific developmental disorders. A zinc finger encoding cDNA (ZNF141) of the C2-H2/KRAB subfamily has been mapped to the 4p- (Wolf-Hirschhorn) syndrome (WHS) chromosome region. ZNF141 was expressed ubiquitously at low levels in the analysed tissue. The identification of a candidate gene for a chromosomal aneusomy syndrome belonging to a class of evolutionary conserved genes will provide options for studying its normal and abnormal expression during mammalian embryogenesis.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZNF141 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

ZNF141 antibody can be used for detection of ZNF141 by ELISA at 1:312500. ZNF141 antibody can be used for detection of ZNF141 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.