NKX2-2 Antibody
Product Specifications
Background
Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
NCBI Gene ID
4821
Swiss Prot
O95096
Accession Number
NP_002500
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NKX2-2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Neuroscience
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1309 - Human Placenta Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NKX2-2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
30 kDa
Applications Notes
NKX2-2 antibody can be used for detection of NKX2-2 by ELISA at 1:1562500. NKX2-2 antibody can be used for detection of NKX2-2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NKX2-2
NCBI Official Name
NK2 homeobox 2
NCBI Organism
Homo sapiens
Background Reference 01
Owen, L.A., (er) PLoS ONE 3 (4), E1965 (2008) .
Other Product Names
NKX2-2, NKX2.2, NKX2B
Tested Applications
ELISA, WB
Protein ID
4505401
Physical Properties
Liquid
Curated Selection
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