ZNF146 Antibody
Product Specifications
Background
ZNF146 (OZF) overexpression in tumours may alter the balance between hRap1 and other telomeric proteins; therefore OZF function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80% of colorectal cancers.
NCBI Gene ID
7705
Swiss Prot
Q15072
Accession Number
NP_009076
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF146.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZNF146 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
33 kDa
Applications Notes
ZNF146 antibody can be used for detection of ZNF146 by ELISA at 1:12500. ZNF146 antibody can be used for detection of ZNF146 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ZNF146
NCBI Official Name
Zinc finger protein 146
NCBI Organism
Homo sapiens
Background Reference 01
Antoine, K., (2005) J. Cell. Biochem. 95 (4), 763-768.
Other Product Names
ZNF146, MGC125660, MGC125661, OZF
Tested Applications
ELISA, WB
Protein ID
153792188
Physical Properties
Liquid
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