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ARC Antibody

Product Specifications

Background

ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.

NCBI Gene ID

23237

Swiss Prot

Q7LC44

Accession Number

NP_056008

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ARC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Applications Notes

ARC antibody can be used for detection of ARC by ELISA at 1:312500. ARC antibody can be used for detection of ARC by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ARC

NCBI Official Name

Activity-regulated cytoskeleton-associated protein

NCBI Organism

Homo sapiens

Background Reference 01

Foo, R.S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (52), 20826-20831.

Other Product Names

ARC, KIAA0278, Arg3.1

Tested Applications

ELISA, WB

Protein ID

8567330

Physical Properties

Liquid

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