SMPD1 Antibody
Product Specifications
Background
SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) .
NCBI Gene ID
6609
Swiss Prot
P17405
Accession Number
NP_000534
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMPD1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Neuroscience
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMPD1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-269
Calculated Molecular Weight
65 kDa
Applications Notes
SMPD1 antibody can be used for detection of SMPD1 by ELISA at 1:62500. SMPD1 antibody can be used for detection of SMPD1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SMPD1
NCBI Official Name
Sphingomyelin phosphodiesterase 1, acid lysosomal
NCBI Organism
Homo sapiens
Background Reference 01
Zeidan, Y.H., (2008) J. Cell Biol. 181 (2), 335-350.
Other Product Names
SMPD1, ASM, NPD, ASMASE
Tested Applications
ELISA, WB
Protein ID
56117840
Physical Properties
Liquid
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