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KCNJ16 Antibody

Product Specifications

Background

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ16 is an integral membrane protein and inward-rectifier type potassium channel. KCNJ16, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

3773

Swiss Prot

Q9NPI9

Accession Number

NP_061128

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNJ16.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KCNJ16 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

48 kDa

Applications Notes

KCNJ16 antibody can be used for detection of KCNJ16 by ELISA at 1:12500. KCNJ16 antibody can be used for detection of KCNJ16 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

KCNJ16

NCBI Official Name

Potassium inwardly-rectifying channel, subfamily J, member 16

NCBI Organism

Homo sapiens

Background Reference 01

Ji, W., (2008) Nat. Genet. 40 (5), 592-599.

Other Product Names

KCNJ16, BIR9, KIR5.1, MGC33717

Tested Applications

ELISA, WB

Protein ID

8923823

Physical Properties

Liquid

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