CNBP Antibody
Product Specifications
Background
CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
7555
Swiss Prot
P62633
Accession Number
NP_003409
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CNBP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CNBP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
19 kDa
Applications Notes
CNBP antibody can be used for detection of CNBP by ELISA at 1:2500. CNBP antibody can be used for detection of CNBP by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CNBP
NCBI Official Name
CCHC-type zinc finger, nucleic acid binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Gerbasi, V.R. (2007) Mol. Cell Proteomics 6 (6), 1049-1058.
Other Product Names
CNBP, CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9
Tested Applications
ELISA, WB
Protein ID
4827071
Physical Properties
Liquid
Curated Selection
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