XK Antibody
Product Specifications
Background
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx) . Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. XK has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx) . Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
7504
Swiss Prot
P51811
Accession Number
NP_066569
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human XK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store XK antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
XK antibody can be used for detection of XK by ELISA at 1:12500. XK antibody can be used for detection of XK by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
XK
NCBI Official Name
X-linked Kx blood group (McLeod syndrome)
NCBI Organism
Homo sapiens
Background Reference 01
Miranda, M., (2007) Mov. Disord. 22 (9), 1358-1361.
Other Product Names
XK, KX, X1k, XKR1, NA, NAC, MCLDS
Tested Applications
ELISA, WB
Protein ID
10835267
Physical Properties
Liquid
Curated Selection
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