MYST2 Antibody

MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MYST2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

MYST2 antibody can be used for detection of MYST2 by ELISA at 1:12500. MYST2 antibody can be used for detection of MYST2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.