MYST2 Antibody
Product Specifications
Background
MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.
NCBI Gene ID
11143
Swiss Prot
O95251
Accession Number
NP_008998
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MYST2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cell Cycle, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
OVCAR-3 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MYST2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-014
Calculated Molecular Weight
71 kDa
Applications Notes
MYST2 antibody can be used for detection of MYST2 by ELISA at 1:12500. MYST2 antibody can be used for detection of MYST2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KAT7
NCBI Official Name
K (lysine) acetyltransferase 7
NCBI Organism
Homo sapiens
Background Reference 01
Wu, Z.Q. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1919-1924.
Other Product Names
MYST2, HBO1, HBOA, KAT7, MYST2, ZC2HC7
Tested Applications
ELISA, WB
Protein ID
5901962
Physical Properties
Liquid
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