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TFCP2 Antibody

Product Specifications

Background

TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

NCBI Gene ID

7024

Swiss Prot

Q12800

Accession Number

NP_005644

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFCP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TFCP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

57 kDa

Applications Notes

TFCP2 antibody can be used for detection of TFCP2 by ELISA at 1:312500. TFCP2 antibody can be used for detection of TFCP2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TFCP2

NCBI Official Name

Transcription factor CP2

NCBI Organism

Homo sapiens

Background Reference 01

Randall, C.N., (er) Neurochem. Res. (2008) In press.

Other Product Names

TFCP2, CP2, LBP-1C, LSF, SEF, TFCP2C, LBP1C, LSF1D

Tested Applications

ELISA, WB

Protein ID

21361278

Physical Properties

Liquid

Frequently Asked Questions

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