CD22 Antibody [hL22 (Epratuzumab) ], Rabbit IgG - Research Grade Biosimilar

Product Specifications

Other Statements

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

NCBI Gene ID

933

Swiss Prot

P20273

Reactivity

Human, Rhesus Monkey, Cynomolgus Monkey

Immunogen

This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5–10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010) .

Clonality

Recombinant Monoclonal

Clone

HL22 (Epratuzumab)

Conjugation

Unconjugated

Type

Primary Antibodies, Biosimilars

Field of Research

Cancer, Immunology, Other

Concentration

Batch dependent

Buffer

PBS with 0.02% Proclin 300.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Fragment

IgG kappa

Symbol

CD22

NCBI Official Name

CD22 molecule

NCBI Organism

Homo sapiens

Other Product Names

Leu14, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14