SARS-COV-2 Nucleocapsid Protein Antibody (biotin) [1B1A9]

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

This antibody can be stored at 2˚ C - 8˚ C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20˚ C to -80˚ C. Preservative-Free.Avoid repeated freeze-thaw cycles.

ELISA Capture: Recommended Concentration:1-4ug/mL, Sample: SARS-CoV-2 Nucleocapsid Protein Antibody (CAP) ELISA Detection: Recommended Concentration:0.05-0.2ug/mL, Sample: Biotinylated SARS-CoV-2 Nucleocapsid Protein Antibody Standard:Recommended Concentration: 1.56-100pg/mL, Sample: Recombinant SARS-COV-2 Nucleocapsid Protein with His tag

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