SARS-COV-2 Nucleocapsid Protein Antibody [9A4B3]
Product Specifications
Background
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
NCBI Gene ID
1489678
Swiss Prot
P0DTC9
Accession Number
QHD43423.2
Host
Rabbit
Reactivity
Virus
Immunogen
E.coli derived SARS-COV-2 Nucleoproteins Ser2-Ala419 (Gly335Ala) Accession #QHD43423.2
Clonality
Recombinant Monoclonal
Clone
9A4B3
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease, COVID-19
Concentration
1 mg/ml
Buffer
Lyophilized from a 0.2 um filtered solution in PBS, pH7.4 with antibody at a final concentration of 1 mg/ml.
Modification
NONE
Shipping Conditions
Room Temp
Storage Conditions
2˚ C - 8˚ C for one month, -20˚ C to -80˚ C for one year. Avoid repeated freeze-thaw cycles
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=24-037
Fragment
Rabbit IgG
Specificity
SARS-COV-2
Applications Notes
ELISA Capture: Recommended Concentration:0.5-2ug/mL, Sample: SARS-CoV-2 Nucleocapsid Protein Antibody (CAP) ELISA Capture: Recommended Concentration:0.005-0.02ug/mL, Sample: SARS-CoV-2 Nucleocapsid Protein Antibody Standard:Recommended Concentration: 156-10000pg/mL, Sample: Recombinant SARS-COV-2 Nucleocapsid Protein with His tag
Symbol
N
NCBI Official Name
Nucleocapsid phosphoprotein
NCBI Organism
SARS-CoV-2
Other Product Names
SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 NP, nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2], novel coronavirus N Protein, novel coronavirus Nucleocapsid Protein, 2019-nCoV Nucleoprotein, 2019-nCoV N, 2019nCoV N, 2019-nCoV N Protein, 2019 peak N Protein, 2019-nCoV nucleocapsid protein.
Tested Applications
ELISA
Physical Properties
Lyophilized
Curated Selection
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