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TMPRSS2 Antibody [ARC2373]

Product Specifications

Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

NCBI Gene ID

7113

Swiss Prot

O15393

Accession Number

O15393

Host

Rabbit

Reactivity

Virus

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Clone

ARC1439

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Modification

NONE

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C short term. Aliquot and store at -20˚ C long term. Avoid freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=24-034

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Symbol

TMPRSS2

NCBI Official Name

Transmembrane serine protease 2

NCBI Organism

Homo sapiens

Other Product Names

PP9284, PRSS10, transmembrane serine protease 2

Tested Applications

WB, IHC

Physical Properties

Liquid

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