OTC Antibody
Product Specifications
Background
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
NCBI Gene ID
5009
Swiss Prot
P00480
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human OTC (NP_000522.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 38kDa
Fragment
IgG
Symbol
OTC
Positive Control 2
Mouse small intestine
Positive Control 3
Rat liver
Positive Control 4
Rat small intestine
NCBI Official Name
Ornithine carbamoyltransferase
NCBI Organism
Homo sapiens
Other Product Names
OTC, OCTD
Tested Applications
WB, IHC
Physical Properties
Liquid
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