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OPA1 Antibody

Product Specifications

Background

This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

4976

Swiss Prot

O60313

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 661-960 of human OPA1 (NP_056375.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Neuroscience

Purification

Affinity purification

Positive Control

NCI-H460

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 90-111kDa

Fragment

IgG

Symbol

OPA1

Positive Control 2

SKOV3

Positive Control 3

Mouse brain

Positive Control 4

Mouse liver

Positive Control 5

Rat brain

NCBI Official Name

OPA1 mitochondrial dynamin like GTPase

NCBI Organism

Homo sapiens

Other Product Names

BERHS, MGM1, MTDPS14, NPG, NTG, largeG, dynamin-like 120 kDa protein, mitochondrial, dynamin-like guanosine triphosphatase, mitochondrial dynamin-like GTPase, optic atrophy 1 (autosomal dominant), optic atrophy protein 1

Tested Applications

WB, IF

Physical Properties

Liquid

Frequently Asked Questions

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