OPA1 Antibody
Product Specifications
Background
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4976
Swiss Prot
O60313
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 661-960 of human OPA1 (NP_056375.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
NCI-H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-931
Calculated Molecular Weight
Observed: 90-111kDa
Fragment
IgG
Symbol
OPA1
Positive Control 2
SKOV3
Positive Control 3
Mouse brain
Positive Control 4
Mouse liver
Positive Control 5
Rat brain
NCBI Official Name
OPA1 mitochondrial dynamin like GTPase
NCBI Organism
Homo sapiens
Other Product Names
BERHS, MGM1, MTDPS14, NPG, NTG, largeG, dynamin-like 120 kDa protein, mitochondrial, dynamin-like guanosine triphosphatase, mitochondrial dynamin-like GTPase, optic atrophy 1 (autosomal dominant), optic atrophy protein 1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
