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MYO5A Antibody

Product Specifications

Background

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

NCBI Gene ID

4644

Swiss Prot

Q9Y4I1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-929

Calculated Molecular Weight

Observed: 240kDa

Fragment

IgG

Symbol

MYO5A

Positive Control 2

Jurkat

Positive Control 3

MCF7

Positive Control 4

HT-1080

Positive Control 5

Mouse spleen

Positive Control 6

Rat brain

NCBI Official Name

Myosin VA (heavy chain 12, myoxin)

NCBI Organism

Homo sapiens

Other Product Names

MYO5A, MYR12, myoxin, myosin, heavy polypeptide kinase, myosin VA (heavy chain 12, myoxin), myosin VA, myosin V, MYO5, MYH12, GS1, dilute

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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