JARID2 Antibody

Product Specifications

Background

This gene encodes a Jumonji- and AT-rich interaction domain (ARID) -domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

NCBI Gene ID

3720

Swiss Prot

Q92833

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1027-1246 of human JARID2 (NP_004964.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

HL-60

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 160kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

JARID2

Positive Control 2

Mouse thymus

Positive Control 3

Rat heart

NCBI Official Name

Jumonji, AT rich interactive domain 2

NCBI Organism

Homo sapiens

Other Product Names

JARID2, jumonji-like protein, jumonji, AT rich interactive domain 2 protein, jumonji homolog, OTTHUMP00000016058, JMJ, AT rich interactive domain 2, JARID2