GRM5 Antibody
Product Specifications
Background
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
2915
Swiss Prot
P41594
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 870-1070 of human GRM5 (NP_001137303.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse skeletal muscle
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 132kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GRM5
Positive Control 2
Rat skeletal muscle
NCBI Official Name
Glutamate receptor, metabotropic 5
NCBI Organism
Homo sapiens
Other Product Names
GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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