GIPR Antibody
Product Specifications
Background
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
NCBI Gene ID
2696
Swiss Prot
P48546
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GIPR
Positive Control 2
Mouse liver
Positive Control 3
Rat heart
Positive Control 4
Rat brain
NCBI Official Name
Gastric inhibitory polypeptide receptor
NCBI Organism
Homo sapiens
Other Product Names
GIPR, MGC126722, HGNC:4271, gastric inhibitory polypeptide receptor, GIPR, PGQTL2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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