COL4A5 Antibody

Product Specifications

Background

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.

NCBI Gene ID

1287

Swiss Prot

P29400

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1462-1691 of human COL4A5 (NP_203699.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

22Rv1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 161kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

COL4A5

Positive Control 2

NCI-H460

Positive Control 3

HepG2

NCBI Official Name

Collagen type IV alpha 5 chain

NCBI Organism

Homo sapiens

Other Product Names

ASLN, ATS, ATS1, CA54, collagen alpha-5 (IV) chain, collagen IV, alpha-5 polypeptide, collagen of basement membrane, alpha-5 chain, collagen, type IV, alpha 5, dA149D17.3, dA24A23.1