LPXN Antibody
Product Specifications
Background
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
9404
Swiss Prot
O60711
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human LPXN (NP_004802.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
LPXN
Positive Control 2
Mouse spleen
Positive Control 3
Rat testis
NCBI Official Name
Leupaxin
NCBI Organism
Homo sapiens
Other Product Names
Leupaxin, LPXN, LDLP
Tested Applications
WB
Physical Properties
Liquid
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