AKR1D1 Antibody

Product Specifications

Background

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta (4) -3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

NCBI Gene ID

6718

Swiss Prot

P51857

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human AKR1D1 (NP_005980.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

MCF7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

AKR1D1

Positive Control 2

HeLa

Positive Control 3

HepG2

Positive Control 4

Mouse liver

NCBI Official Name

3-oxo-5-beta-steroid 4-dehydrogenase

NCBI Organism

Homo sapiens

Other Product Names

3-oxo-5-beta-steroid 4-dehydrogenase, Aldo-keto reductase family 1 member D1, Delta (4) -3-ketosteroid 5-beta-reductase, Delta (4) -3-oxosteroid 5-beta-reductase, AKR1D1, SRD5B1