IMPDH1 Antibody
Product Specifications
Background
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP) . This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10) . Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
3614
Swiss Prot
P20839
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_899066.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
IMPDH1
Positive Control 2
BT-474
Positive Control 3
HL-60
Positive Control 4
22Rv1
Positive Control 5
HT-29
Positive Control 6
Mouse brain
NCBI Official Name
IMP (inosine 5'-monophosphate) dehydrogenase 1
NCBI Organism
Homo sapiens
Other Product Names
IMPDH1, DKFZp781N0678, IMPD, IMPD1, LCA11, RP10, sWSS2608
Tested Applications
WB
Physical Properties
Liquid
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