PCCA Antibody
Product Specifications
Background
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5095
Swiss Prot
P05165
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA (NP_000273.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse pancreas
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:3000
Symbol
PCCA
Positive Control 2
Mouse liver
Positive Control 3
Mouse brain
Positive Control 4
Mouse kidney
Positive Control 5
Rat kidney
NCBI Official Name
Propionyl CoA carboxylase, alpha polypeptide
NCBI Organism
Homo sapiens
Other Product Names
PCCA
Tested Applications
WB
Physical Properties
Liquid
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