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DSG2 Antibody

Product Specifications

Background

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

NCBI Gene ID

1829

Swiss Prot

Q14126

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 150kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

DSG2

Positive Control 2

HeLa

Positive Control 3

SW620

Positive Control 4

DU145

Positive Control 5

K-562

NCBI Official Name

Desmoglein 2

NCBI Organism

Homo sapiens

Other Product Names

DSG2, ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037, CMD1BB

Tested Applications

WB

Physical Properties

Liquid

Curated Selection

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