IYD Antibody
Product Specifications
Background
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
389434
Swiss Prot
Q6PHW0
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 24-214 of human IYD (NP_981932.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Mouse lung
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-810
Calculated Molecular Weight
Observed: 25kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
IYD
Positive Control 2
Mouse pancreas
NCBI Official Name
Iodotyrosine deiodinase
NCBI Organism
Homo sapiens
Other Product Names
C6orf71, DEHAL1-1, TDH4, IYD, iodotyrosine deiodinase 1, iodotyrosine dehalogenase 1
Tested Applications
WB
Physical Properties
Liquid
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