PDGFRL Antibody
Product Specifications
Background
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
NCBI Gene ID
5157
Swiss Prot
Q15198
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 15-205 of human PDGFRL (NP_006198.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
NCI-H125
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
PDGFRL
Positive Control 2
Mouse brain
NCBI Official Name
Platelet-derived growth factor receptor-like
NCBI Organism
Homo sapiens
Other Product Names
PDGFRL, PDGRL, PRLTS, PDGFR-like protein
Tested Applications
WB
Physical Properties
Liquid
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