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MTMR2 Antibody

Product Specifications

Background

This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.

NCBI Gene ID

8898

Swiss Prot

Q13614

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 404-643 of human MTMR2 (NP_057240.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=23-770

Calculated Molecular Weight

Observed: 65-73kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MTMR2

Positive Control 2

Jurkat

Positive Control 3

U-87MG

Positive Control 4

Mouse brain

Positive Control 5

Mouse kidney

Positive Control 6

Mouse liver

NCBI Official Name

Myotubularin related protein 2

NCBI Organism

Homo sapiens

Other Product Names

CMT4B, CMT4B1, myotubularin-related protein 2, phosphatidylinositol-3,5-bisphosphate 3-phosphatase, phosphatidylinositol-3-phosphatase, phosphatidylinositol-3-phosphate phosphatase, phosphoinositide-3-phosphatase

Tested Applications

WB

Physical Properties

Liquid

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