CNOT7 Antibody
Product Specifications
Background
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.
NCBI Gene ID
29883
Swiss Prot
Q9UIV1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
CNOT7
Positive Control 2
U-87MG
Positive Control 3
HT-29
Positive Control 4
Raji
Positive Control 5
HeLa
Positive Control 6
Mouse lung
NCBI Official Name
CCR4-NOT transcription complex, subunit 7
NCBI Organism
Homo sapiens
Other Product Names
CNOT7, CAF1, Caf1a, hCAF-1
Tested Applications
WB
Physical Properties
Liquid
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