NPHP4 Antibody
Product Specifications
Background
This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
261734
Swiss Prot
O75161
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1247-1426 of human NPHP4 (NP_055917.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 157kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NPHP4
Positive Control 2
A-549
NCBI Official Name
Nephrocystin 4
NCBI Organism
Homo sapiens
Other Product Names
POC1SLSN4, nephrocystin-4, POC10 centriolar protein homolog, nephroretinin
Tested Applications
WB
Physical Properties
Liquid
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