SHPK Antibody
Product Specifications
Background
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
NCBI Gene ID
23729
Swiss Prot
Q9UHJ6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human SHPK (NP_037408.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
A375
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
SHPK
Positive Control 2
Mouse kidney
Positive Control 3
Rat testis
NCBI Official Name
Sedoheptulokinase
NCBI Organism
Homo sapiens
Other Product Names
CARKL, SHK, sedoheptulokinase, carbohydrate kinase-like protein
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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