NUP133 Antibody
Product Specifications
Background
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.
NCBI Gene ID
55746
Swiss Prot
Q8WUM0
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 730-930 of human NUP133 (NP_060700.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A375
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 133kDa
Fragment
IgG
Symbol
NUP133
Positive Control 2
LO2
Positive Control 3
HeLa
Positive Control 4
NCI-H460
NCBI Official Name
Nucleoporin 133
NCBI Organism
Homo sapiens
Other Product Names
GAMOS8, NPHS18, hNUP133, nuclear pore complex protein Nup133, 133 kDa nucleoporin, nucleoporin 133kD, nucleoporin 133kDa, nucleoporin Nup133
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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