THOP1 Antibody
Product Specifications
Background
The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.
NCBI Gene ID
7064
Swiss Prot
P52888
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THOP1 (NP_003240.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
Mouse skeletal muscle
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 79kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
THOP1
Positive Control 2
Mouse heart
Positive Control 3
Mouse lung
Positive Control 4
Rat liver
Positive Control 5
Rat kidney
NCBI Official Name
Thimet oligopeptidase 1
NCBI Organism
Homo sapiens
Other Product Names
EP24.15, MEPD_HUMAN, MP78, TOP, thimet oligopeptidase, endopeptidase 24.15
Tested Applications
WB
Physical Properties
Liquid
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