GDI2 Antibody, KO Validated
Product Specifications
Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
2665
Swiss Prot
P50395
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 296-445 of human GDI2 (NP_001485.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 51kDa
Fragment
IgG
Symbol
GDI2
Positive Control 2
A-549
Positive Control 3
HepG2
Positive Control 4
U-87MG
Positive Control 5
Mouse spleen
Positive Control 6
Mouse kidney
NCBI Official Name
GDP dissociation inhibitor 2
NCBI Organism
Homo sapiens
Other Product Names
GDI2, RABGDIB, HEL-S-46e
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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