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HERC3 Antibody

Product Specifications

Background

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

NCBI Gene ID

8916

Swiss Prot

Q15034

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HERC3 (NP_055421.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 117kDa

Fragment

IgG

Symbol

HERC3

Positive Control 2

U-87MG

Positive Control 3

A-431

Positive Control 4

Mouse lung

Positive Control 5

Mouse spinal cord

NCBI Official Name

Probable E3 ubiquitin-protein ligase HERC3

NCBI Organism

Homo sapiens

Other Product Names

Probable E3 ubiquitin-protein ligase HERC3, 632-, HECT domain and RCC1-like domain-containing protein 3, HERC3, KIAA0032

Tested Applications

WB, IHC

Physical Properties

Liquid

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