ACAN Antibody
Product Specifications
Background
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
NCBI Gene ID
176
Swiss Prot
P16112
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human ACAN (NP_001126.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 100kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ACAN
Positive Control 2
HepG2
Positive Control 3
Mouse liver
Positive Control 4
Mouse brain
NCBI Official Name
Aggrecan
NCBI Organism
Homo sapiens
Other Product Names
ACAN, AGCAN, Aggrecan core protein, Acg1, Aggrecan, CSPG1, CSPGCP, CSPCP, AGC1, Aggrecan 1, Large aggregating proteoglycan, MSK16, SEDK, MCSPG
Tested Applications
WB
Physical Properties
Liquid
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