PTPRU Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.
NCBI Gene ID
10076
Swiss Prot
Q92729
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1184-1433 of human PTPRU (NP_001181930.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Rat brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-609
Calculated Molecular Weight
Observed: 180kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PTPRU
NCBI Official Name
Protein tyrosine phosphatase receptor type U
NCBI Organism
Homo sapiens
Other Product Names
FMI, PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, PTPU2, R-PTP-PSI, R-PTP-U, hPTP-J, receptor-type tyrosine-protein phosphatase U, PTP pi, Receptor protein tyrosine phosphatase hPTP-J, pancreatic carcinoma phosphatase 2, pi R-PTP-Psi, protein-tyrosine phosphatase J, protein-tyrosine phosphatase pi, protein-tyrosine phosphatase receptor omicron, receptor-type protein-tyrosine phosphatase psi
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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