F2RL3 Antibody

Product Specifications

Background

Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

NCBI Gene ID

9002

Swiss Prot

Q96RI0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human F2RL3 (NP_003941.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 41kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

F2RL3

Positive Control 2

HT-29

Positive Control 3

Raji

Positive Control 4

B cells

Positive Control 5

Mouse spleen

Positive Control 6

Mouse lung

NCBI Official Name

F2R like thrombin or trypsin receptor 3

NCBI Organism

Homo sapiens

Other Product Names

PAR4, proteinase-activated receptor 4, F2R like thrombin/trypsin receptor 3, PAR-4, coagulation factor II (thrombin) receptor-like 3, protease-activated receptor-4, thrombin receptor-like 3