DSPP Antibody
Product Specifications
Background
This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene.
NCBI Gene ID
1834
Swiss Prot
Q9NZW4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 16-146 of human DSPP (NP_055023.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
DSPP
Positive Control 2
HL-60
NCBI Official Name
Dentin sialophosphoprotein
NCBI Organism
Homo sapiens
Other Product Names
DFNA39, DGI1, DMP3, DPP, DSP, dentin sialophosphoprotein, dentin phosphophoryn, dentin phosphoprotein, dentin phosphoryn, dentin sialoprotein
Tested Applications
WB
Physical Properties
Liquid
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