CRHR1 Antibody
Product Specifications
Background
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.
NCBI Gene ID
1394
Swiss Prot
P34998
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 24-120 of human CRHR1 (NP_001138618.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Obesity, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-564
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
CRHR1
Positive Control 2
SH-SY5Y
Positive Control 3
HT-29
Positive Control 4
HeLa
Positive Control 5
Mouse brain
Positive Control 6
Mouse liver
NCBI Official Name
Corticotropin releasing hormone receptor 1
NCBI Organism
Homo sapiens
Other Product Names
CRHR1, corticotropin releasing hormone receptor 1, CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f, corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor, CRFR
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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